Gel Electrophoresis Reagents and Buffers
Cayman Chemical KB-0742hydrochlorIde 50mg
A Cdk9 inhibitor (IC50 = 6 nM); selective for Cdk9 over Cdk1-8 (IC50s = 397->10,000 nM) and Cdk12-19 (IC50s = 372->10,000 nM); induces cell cycle arrest at the G1 phase and apoptosis in BT-20, BT-549, MDA-MB-231, MT-3, and Hs 578T TNBC cells from 0.64-7.73 µM; reduces tumor volume in the MYC-amplified CTG-0437 PDX mouse model of TNBC at 60 mg/kg
Cayman Chemical KB-0742hydrochlorIde 5mg
A Cdk9 inhibitor (IC50 = 6 nM); selective for Cdk9 over Cdk1-8 (IC50s = 397->10,000 nM) and Cdk12-19 (IC50s = 372->10,000 nM); induces cell cycle arrest at the G1 phase and apoptosis in BT-20, BT-549, MDA-MB-231, MT-3, and Hs 578T TNBC cells from 0.64-7.73 µM; reduces tumor volume in the MYC-amplified CTG-0437 PDX mouse model of TNBC at 60 mg/kg
Cell Signaling Technology Blue Prestained Protein Marker Detection Pack 1 Kit
Blue Prestained Protein Marker Detection Pack 1 Kit
Bioworld Immunoprecipitation (IP) Buffer, 50 mL
Immunoprecipitation bufferContains:NaCl, Tris-HCl pH-7.4, DTT, NP40, glycerol plus protease inhibitors.
ABclonal Technology EMC1 Rabbit pAb
This gene encodes a single-pass type I transmembrane protein, which is a subunit of the endoplasmic reticulum membrane protein complex (EMC). Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
ABclonal Technology CYBA Rabbit pAb
Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells.
ABclonal Technology CSK Rabbit pAb
The protein encoded by this gene is involved in multiple pathways, including the regulation of Src family kinases. It plays an important role in T-cell activation through its association with the protein encoded by the protein tyrosine phosphatase, non-receptor type 22 (PTPN22) gene. This protein also phosphorylates C-terminal tyrosine residues on multiple substrates, including the protein encoded by the SRC proto-oncogene, non-receptor tyrosine kinase gene. Phosphorylation suppresses the kinase activity of the Src family tyrosine kinases. An intronic polymorphism (rs34933034) in this gene has been found to affect B-cell activation and is associated with systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants.
ABclonal Technology OTUB1 Rabbit pAb
The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants.
ABclonal Technology CACNA2D3 Rabbit pAb
This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1111 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Biochain Institute Inc 100 bp DNA Ladder Plus, ready-to-use, 50 ug, 0.5 ug per lane, 100 lanes/PK
BioChain provides a series of molecular weight markers, including DNA markers, RNA markers, and protein markers, to accurately determine the size of your DNA, RNA, and protein on the separation gels.
Biochain Institute Inc 100 bp DNA Ladder Plus, loading dye included, 250 ug, 0.5 ug per lane, 500 lanes/PK
BioChain provides a series of molecular weight markers, including DNA markers, RNA markers, and protein markers, to accurately determine the size of your DNA, RNA, and protein on the separation gels.